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| zaterdag 07/08/21 | SK St-Niklaas | - | K.OLSA Brakel | afg | |||
| woensdag 11/08/21 | SV Zulte-Waregem (El) | - | K.OLSA Brakel | 5 | - | 4 | |
| zaterdag 14/08/21 | 13u30 | K.OLSA Brakel | - | KSV Oostkamp | 4 | - | 4 |
| zaterdag 21/08/21 | 10u00 | FCV Dender EH | - | K.OLSA Brakel | 2 | - | 3 |
| zaterdag 28/08/21 | 13u30 | K.OLSA Brakel | - | Tempo Overijse | 7 | - | 2 |
| dinsdag 12/10/21 | 19u00 | KAA Gent (EU14) | - | K.OLSA Brakel | 5 | - | 4 |
| zaterdag 04/09/21 | 11u30 | K.OLSA BRAKEL | - | KM TORHOUT | 3 | - | 1 |
| zaterdag 11/09/21 | 14u30 | KSV OUDENAARDE | - | K.OLSA BRAKEL | 0 | - | 7 |
| zaterdag 18/09/21 | 16u30 | K.OLSA BRAKEL | - | KFC SPARTA PETEGEM | 2 | - | 0 |
| zaterdag 25/09/21 | 12u30 | FC MU IZEG.-INGELM. | - | K.OLSA BRAKEL | 2 | - | 0 |
| zaterdag 02/10/21 | 14u00 | K.OLSA BRAKEL | - | KVK AVELGEM | 9 | - | 1 |
| zaterdag 09/10/21 | 14u00 | K.OLSA BRAKEL | - | KRC GENT | 4 | - | 3 |
| zaterdag 16/10/21 | 15u15 | KVK WESTHOEK | - | K.OLSA BRAKEL | 4 | - | 4 |
| zaterdag 23/10/21 | 15u15 | KM TORHOUT | - | K.OLSA BRAKEL | 5 | - | 1 |
| zaterdag 30/10/21 | 14u00 | K.OLSA BRAKEL | - | KSV OUDENAARDE | 4 | - | 4 |
| zaterdag 06/11/21 | 15u15 | KFC SPARTA PETEGEM | - | K.OLSA BRAKEL | 3 | - | 1 |
| zaterdag 13/11/21 | 13u30 | K.OLSA BRAKEL | - | FC MU IZEG.-INGELM. | 2 | - | 3 |
| zaterdag 20/11/21 | 14u00 | KVK AVELGEM | - | K.OLSA BRAKEL | 5 | - | 1 |
| zaterdag 27/11/21 | 14u00 | KRC GENT | - | K.OLSA BRAKEL | uitg | ||
| zaterdag 04/12/21 | 13u30 | K.OLSA BRAKEL | - | KVK WESTHOEK | uitg | ||
| zaterdag 11/12/21 | BYE | ||||||
| zaterdag 18/12/21 | BYE | ||||||
| zaterdag 25/12/21 | BYE |
| zaterdag 08/01/22 | 14u00 | K.OLSA BRAKEL | - | K.V.K. WESTHOEK A | 2 | - | 2 |
| zaterdag 15/01/22 | 15u15 | KM TORHOUT A | - | K.OLSA BRAKEL | 4 | - | 5 |
| zaterdag 22/01/22 | 15u30 | K.OLSA BRAKEL | - | K.S.V. ROESELARE | uitg | ||
| zaterdag 29/01/22 | 14u45 | FC GULLEGEM A | - | K.OLSA BRAKEL | 6 | - | 1 |
| zaterdag 05/02/22 | 13u30 | K.OLSA BRAKEL | - | RAC. CLUB HARELBEKE A | 7 | - | 2 |
| zaterdag 12/02/22 | 14u30 | K.S.V. OUDENAARDE A | - | K.OLSA BRAKEL | 1 | - | 3 |
| zaterdag 19/02/22 | 13u30 | K.OLSA BRAKEL | - | FC MU IZEG.-INGELM. A | 3 | - | 2 |
| zaterdag 26/02/22 | BYE | ||||||
| zaterdag 05/03/22 | 15u15 | K.V.K. WESTHOEK A | - | K.OLSA BRAKEL | 4 | - | 1 |
| zaterdag 12/03/22 | 13u30 | K.OLSA BRAKEL | - | KM TORHOUT A | 2 | - | 2 |
| zaterdag 19/03/22 | 14u30 | K.S.V. ROESELARE | - | K.OLSA BRAKEL | 2 | - | 1 |
| zaterdag 26/03/22 | 13u30 | K.OLSA BRAKEL | - | FC GULLEGEM A | 1 | - | 3 |
| zaterdag 02/04/22 | 14u00 | RAC. CLUB HARELBEKE A | - | K.OLSA BRAKEL | 1 | - | 4 |
| zaterdag 09/04/22 | 13u30 | K.OLSA BRAKEL | - | K.S.V. OUDENAARDE A | - | ||
| zaterdag 16/04/22 | BYE | ||||||
| zaterdag 23/04/22 | 12u30 | FC MU IZEG.-INGELM. A | - | K.OLSA BRAKEL | - | ||
| zaterdag 30/04/22 | BYE |
| Ploeg | M | W | V | G | + | - | +/- | PTN | |
| 1 | K.V.K. WESTHOEK A | 13 | 10 | 1 | 2 | 47 | 24 | 23 | 32 |
| 2 | KM TORHOUT A | 14 | 9 | 5 | 0 | 37 | 32 | 5 | 27 |
| 3 | K.F.C. SPARTA PETEGEM A | 14 | 7 | 7 | 0 | 39 | 35 | 4 | 21 |
| 4 | RACING CLUB GENT | 13 | 6 | 5 | 2 | 49 | 32 | 17 | 20 |
| 5 | K. OLSA BRAKEL | 12 | 5 | 5 | 2 | 38 | 31 | 7 | 17 |
| 5 | K.V.K. AVELGEM A | 14 | 5 | 7 | 2 | 26 | 38 | -12 | 17 |
| 7 | FC MU IZEGEM-INGELMUNSTER A | 14 | 4 | 9 | 1 | 22 | 37 | -15 | 13 |
| 8 | K.S.V. OUDENAARDE A | 14 | 1 | 8 | 5 | 28 | 57 | -29 | 8 |
| Ploeg | M | W | V | G | + | - | +/- | PTN | |
| 1 | K.V.K. WESTHOEK A | 12 | 8 | 2 | 2 | 37 | 14 | 23 | 26 |
| 2 | KM TORHOUT A | 11 | 7 | 2 | 2 | 37 | 19 | 18 | 23 |
| 3 | FOOTBALL CLUB GULLEGEM A | 12 | 5 | 4 | 3 | 28 | 25 | 3 | 18 |
| 3 | FC MU IZEGEM-INGELMUNSTER A | 12 | 5 | 4 | 3 | 22 | 19 | 3 | 18 |
| 5 | K. OLSA BRAKEL | 11 | 5 | 4 | 2 | 30 | 29 | 1 | 17 |
| 6 | K.SV.ROESELARE | 10 | 4 | 4 | 2 | 18 | 17 | 1 | 14 |
| 7 | K.S.V. OUDENAARDE A | 12 | 4 | 8 | 0 | 26 | 42 | -16 | 12 |
| 8 | RACING CLUB HARELBEKE A | 12 | 1 | 11 | 0 | 13 | 46 | -33 | 3 |
